[Expression and mutation of myc antagonist genes Mad1, Mxi1 and Rox in leukemia cells].

Article

[Expression and mutation of myc antagonist genes Mad1, Mxi1 and Rox in leukemia cells].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Nov 2007

Suo Xiao-Hui, Pan Ling, Yao Li, Zhang Xue-Jun, Niu Zhi-Yun, Dong Zuo-Ren

Abstract excerpt

OBJECTIVE: To investigate the expression and mutation of Mad1, Mxi1 and Rox genes in leukemia cells. METHODS: Expression and mutation of Mad1, Mxi1 and Rox genes in bone marrow mononuclear cells (BMMNC) from 26 de novo acute leukemia (AL) patients, and in peripheral blood mononuclear cells (PBMNC) from 30 healthy volunteers, as well as in 7 human leukemic cell lines were analyzed by reverse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins

Share to Leukemia

Share to Nuclear Proteins

Share to Polymorphism, Single-Stranded Conformational

Share to Repressor Proteins

Share to Tumor Suppressor Proteins

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

[Expression and mutation of myc antagonist genes Mad1, Mxi1 and Rox in leukemia cells].PMID 18457265Read

ROR1: an orphan becomes apparentSemantic proximity Read

[IDH gene mutations and acute myeloid leukemia].Semantic proximity Read

Research progress on gene mutations and drug resistance in leukemia.Semantic proximity Read

[Molecular pathogenesis of acute myeloid leukemia].Semantic proximity Read

Targeting ROR1 identifies new treatment strategies in hematological cancersSemantic proximity Read

Meis1 is critical to the maintenance of human acute myeloid leukemia cells independent of MLL rearrangementsSemantic proximity Read

Novel therapeutic strategies for MLL-rearranged leukemias.Semantic proximity Read

[Genomic instability in leukemia].Semantic proximity Read