Article
The anti-HIV activity of entecavir: a multicentre evaluation of lamivudine-experienced and lamivudine-naive patients.
AIDS (London, England) - 11 May 2008
Sasadeusz Joe, Audsley Jennifer, Mijch Anne, Baden Rachel, Caro Jose, Hunter Hermeyone, Matthews Gail, McMahon Moira A, Olender Susan A, Siliciano Robert F, Lewin Sharon R, Thio Chloe L
Abstract excerpt
BACKGROUND: Entecavir, an antiviral with potent anti-hepatitis B virus activity, was recently shown to have anti-HIV activity in three patients and the ability to select for the lamivudine-resistant HIV polymerase mutation M184V in a patient with prior antiretroviral therapy. OBJECTIVES: To further characterize entecavir's anti-HIV activity and identify risk factors for selection of the M184V. DESIGN:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.