Article
Study of the genetic heterogeneity of SAT-2 foot-and-mouth disease virus in sub-Saharan Africa with specific focus on East Africa.
The Onderstepoort journal of veterinary research - 1 Dec 2007
Sahle M, Dwarka R M, Venter E H, Vosloo W
Abstract excerpt
The epidemiology of serotype SAT-2 foot-and-mouth disease was investigated in sub-Saharan Africa by phylogenetic analysis using the 1D gene encoding the major antigenic determinant. Fourteen genotypes were identified of which three are novel and belong to East Africa, bringing the total number of genotypes for that region to eight. The genotypes clustered into three lineages that demonstrated surprising links...
Topics
- Africa, Eastern
- Amino Acid Sequence
- Animals
- Base Sequence
- Cluster Analysis
- DNA, Viral
- Disease Outbreaks
- Epitopes
- Foot-and-Mouth Disease
- Foot-and-Mouth Disease Virus
- Gene Amplification
- Genetic Variation
- Genotype
- Molecular Sequence Data
- Mutation
- Phylogeny
- RNA, Viral
- Sequence Alignment