Article
The apolipoprotein E2 isoform is associated with accelerated onset of coronary artery disease in systemic lupus erythematosus.
Medical science monitor : international medical journal of experimental and clinical research - 1 May 2008
Orlacchio Antonio, Bruce Ian N, Rahman Proton, Kawarai Toshitaka, Bernardi Giorgio, St George-Hyslop Peter H, Gladman Dafna D, Urowitz Murray B
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is a highly prevalent autoimmune disease and coronary artery disease (CAD) is a complication of SLE which is often crucial for the patient's prognosis. It is hypothesized that apolipoprotein E (Apo E), which is involved in cholesterol metabolism, mig...
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