Article
Molecular analysis of factor IX gene in an Iranian female with severe hemophilia B.
Acta haematologica - 1 Jan 2008
Karimipoor Morteza, Kokabee Leila, Kamali Esmat, Karizi Shohreh Zare, Zeinali Sirous
Abstract excerpt
Hemophilia B, a recessive X-linked coagulopathy, is rare in females, and only a few cases have been reported so far. In this report, we describe a 9-year-old female, offspring of a consanguineous marriage, with a clinically severe course of hemophilia B and a normal 46,XX karyotype. Polymerase chain reaction and conformation sensitive gel electrophoresis techniques have been applied to the important regions of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.