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Article

Factor IX mutations in haemophilia B patients in Malaysia: a preliminary study.

The Malaysian journal of pathology - 1 Jun 2012

Balraj Pauline, Ahmad Munirah, Khoo Alan Soo Beng, Ayob Yasmin

Abstract excerpt

Haemophilia B is caused by coagulation defects in the factor IX gene located in Xq27.1 on the X chromosome. Identification of mutations contributing to defective factor IX may be advantageous for precise carrier and prenatal diagnosis. We studied 16 patients from 11 families, consisting of 8 patients of the Malay ethnic group, of which 6 were siblings. Factor IX mutations have not been previously reported in the...

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PMID: 22870602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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