Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer: a profit-driven biosystem?

Medical hypotheses - 1 Aug 2008

Deisboeck Thomas S

Abstract excerpt

The argument is made that solid malignant tumors behave as profit-driven biological systems in that they expand their nutrient-uptaking surface to increase energetic revenue, at a comparably low metabolic cost. Within this conceptual framework, cancer cell migration is a critical mechanism as it maximizes systemic surface expansion while minimizing diffusion distance. Treating these tumor systems with adjuvant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neoplasms
Share to Neovascularization, Pathologic
Share to Treatment Outcome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antineoplastic Agents

Share to Cell Movement

Share to Cell Proliferation

Share to Medical Oncology

Share to Models, Theoretical

Source

Open in PubMed Open full text

Identifiers

PMID: 18420354
DOI: 10.1016/j.mehy.2008.02.010
PMCID: PMC2504025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Cancer: a profit-driven biosystem?PMID 18420354Read ↗

Understanding and leveraging phenotypic plasticity during metastasis formation.Semantic proximity Read ↗

Understanding and leveraging phenotypic plasticity during metastasis formationSemantic proximity Read ↗

Recurring Cycles of Deprivation of Serum and Migration in Confined Spaces Augments Ganglioside SSEA-4 Expression, Boosting Clonogenicity andCisplatin Resistance in TNBC Cell LineSemantic proximity Read ↗

A phenotype-structured model to reproduce the avascular growth of a tumor and its interaction with the surrounding environment.Semantic proximity Read ↗

Evolutionary emergence of angiogenesis in avascular tumors using a spatial public goods game.Semantic proximity Read ↗

Sweat but no gain: Inhibiting proliferation of multidrug resistant cancer cells with “ersatzdroges”Semantic proximity Read ↗

Modeling VEGF and GLUT1 Expression as Coadapted Foraging Strategies in CancerSemantic proximity Read ↗

[Cancer Cells as Dynamic System - Molecular and Phenotypic Changes During Tumor Formation, Progression and Dissemination].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.