Article
Proteomic identification of the Cus system as a major determinant of constitutive Escherichia coli silver resistance of chromosomal origin.
Journal of proteome research - 1 Jun 2008
Lok Chun-Nam, Ho Chi-Ming, Chen Rong, Tam Paul Kwong-Hang, Chiu Jen-Fu, Che Chi-Ming
Abstract excerpt
Although silver is one of the most potent and rapidly acting toxic metals to bacteria, silver-resistant bacteria do exist with low incidence. A proteomic approach was employed to identify the silver resistance determinants of a silver-resistant Escherichia coli strain isolated from stepwise selection against increasing concentrations of silver (Li et al. J. Bacteriol 1997, 179, 6127-32). Two-dimensional gel...
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