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Article

Glycosylation site binding protein and protein disulfide isomerase are identical and essential for cell viability in yeast.

Proceedings of the National Academy of Sciences of the United States of America - 15 May 1991

LaMantia M, Miura T, Tachikawa H, Kaplan H A, Lennarz W J, Mizunaga T

Abstract excerpt

Glycosylation site binding protein (GSBP) has been shown to be identical to protein disulfide isomerase (PDI; EC 5.3.4.1) in a variety of multicellular organisms. We have utilized immunological and biochemical techniques to determine if GSBP and PDI are identical in yeast. Antiserum prepared against yeast GSBP identified in microsomes by its ability to be labeled with a peptide photoaffinity probe was found to...

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Identifiers

PMID: 1840696
DOI: 10.1073/pnas.88.10.4453
PMCID: PMC51678

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