Article
Interpreting changes in measles genotype: the contribution of chance, migration and vaccine coverage.
BMC infectious diseases - 11 Apr 2008
Nojiri Shuko, Vynnycky Emilia, Gay Nigel
Abstract excerpt
BACKGROUND: In some populations, complete shifts in the genotype of the strain of measles circulating in the population have been observed, with given genotypes being replaced by new genotypes. Studies have postulated that such shifts may be attributable to differences between the fitness of the new and the old genotypes. METHODS: We developed a stochastic model of the transmission dynamics of measles, simulating...
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