Article
Evolution of non-cytotoxic uterine natural killer cells.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 May 2008
Kalkunte Satyan, Chichester Clinton O, Gotsch Francesca, Sentman Charles L, Romero Roberto, Sharma Surendra
Abstract excerpt
The immune tolerance and de novo vascularization are two highly intriguing processes at the maternal-fetal interface that appear to be central to normal pregnancy outcome. Immune tolerance occurs despite the local presence of an active maternal immune system including macrophages, dendritic cells and specialized CD56(bright)CD16(-) uterine natural killer (uNK) cells (65-70%). Recent observations indicate that the...
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