Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autism: the role of cholesterol in treatment.

International review of psychiatry (Abingdon, England) - 1 Apr 2008

Aneja Alka, Tierney Elaine

Abstract excerpt

Cholesterol is essential for neuroactive steroid production, growth of myelin membranes, and normal embryonic and fetal development. It also modulates the oxytocin receptor, ligand activity and G-protein coupling of the serotonin-1A receptor. A deficit of cholesterol may perturb these biological mechanisms and thereby contribute to autism spectrum disorders (ASDs), as observed in Smith-Lemli-Opitz syndrome (SLOS)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autistic Disorder
Share to Child
Share to Cholesterol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Smith-Lemli-Opitz Syndrome

Source

Identifiers

PMID: 18386207
DOI: 10.1080/09540260801889062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autism: the role of cholesterol in treatment.PMID 18386207Read ↗

Development, behavior, and biomarker characterization of Smith-Lemli-Opitz syndrome: an updateSemantic proximity Read ↗

Cholesterol alterations in fragile X syndrome, autism spectrum disorders and other neurodevelopmental disorders.Semantic proximity Read ↗

Smith-Lemli-Opitz syndrome: phenotype, natural history, and epidemiology.Semantic proximity Read ↗

Cholesterol and development: the RSH ("Smith-Lemli-Opitz") syndrome and related conditions.Semantic proximity Read ↗

Pharmacological, non-pharmacological and stem cell therapies for the management of autism spectrum disorders: A focus on human studies.Semantic proximity Read ↗

Smith-Lemli-Opitz syndrome: the first malformation syndrome associated with defective cholesterol synthesis.Semantic proximity Read ↗

Dietary interventions in children with autism spectrum disorders - an updated review of the research evidence.Semantic proximity Read ↗

RSH/Smith-Lemli-Opitz syndrome: a multiple congenital anomaly/mental retardation syndrome due to an inborn error of cholesterol biosynthesis.Semantic proximity Read ↗

Safety and efficacy of orally administered full-spectrum medicinal cannabis plant extract 0.08% THC (NTI-164) in children with autism spectrum disorder: An open-label studySemantic proximity Read ↗

[Inborn error of cholesterol biosynthesis: Smith-Lemli-Opitz syndrome].Semantic proximity Read ↗

Pharmacological Interventions in Autism Spectrum Disorder: A Comprehensive Review of Mechanisms and EfficacySemantic proximity Read ↗

Towards the convergent therapeutic potential of GPCRs in autism spectrum disordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.