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Article

Identification of a sterol mutant of Neurospora crassa deficient in delta 14,15-reductase activity.

Journal of general microbiology - 1 Nov 1991

Ellis S W, Rose M E, Grindle M

Abstract excerpt

A mutant (erg-3) of Neurospora crassa resistant to the polyene antibiotic nystatin was compared with its sensitive, wild-type parent to detect differences in sterol composition using gas chromatography-mass spectrometry. The major sterol in wild-type mycelia, comprising 80% of the total, was ergosterol. The major sterols in mutant mycelia, comprising 86% of the total, were delta 8,14-sterols. It is proposed that...

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PMID: 1838392
DOI: 10.1099/00221287-137-11-2627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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