Article
The modifying effect of C-reactive protein gene polymorphisms on the association between central obesity and endometrial cancer risk.
Cancer - 1 Jun 2008
Wen Wanqing, Cai Qiuyin, Xiang Yong-Bing, Xu Wang-Hong, Ruan Zhi Xian, Cheng Jiarong, Zheng Wei, Shu Xiao-Ou
Abstract excerpt
BACKGROUND: Obesity is a major risk factor for endometrial cancer. Obesity, particularly central obesity, is considered as a systemic inflammatory condition and is related strongly to insulin resistance. C-reactive protein (CRP) is the most recognized biologic marker of chronic systematic inflammation, and it is conceivable that the CRP gene may work together with obesity in the development of endometrial cancer....
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