Article
Persistence of pathogens despite clinical improvement in antibiotic-treated acute otitis media is associated with clinical and bacteriologic relapse.
The Pediatric infectious disease journal - 1 Apr 2008
Asher Elad, Dagan Ron, Greenberg David, Givon-Lavi Noga, Libson Shai, Porat Nurith, Leiberman Alberto, Leibovitz Eugene
Abstract excerpt
BACKGROUND: Pathogen eradication in patients with acute otitis media (AOM) is associated with a reduced risk of clinical failures, but most children in whom middle ear fluid (MEF) culture remains positive show clinical improvement or clinical cure. We investigated the relationship between MEF culture-positivity during treatment in patients with clinical improvement/cure, and the occurrence of subsequent AOM....
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