Article
Genetic alteration of penicillin non-susceptible Streptococcus pneumoniae observed throughout recurrence of acute otitis media detected by amplified fragment length polymorphism analysis.
Acta medica Okayama - 1 Jun 2001
Sugata K, Fukushima K, Ogawa T, Nakashima T, Sugata A, Kasai N, Gunduz M, Ueki Y, Nishizaki K
Abstract excerpt
The prevalence of penicillin non-susceptible Streptococcus pneumoniae (PNSSP) is increasing among isolates from acute otitis media (AOM). Repeated episodes of antibiotic exposure are a well-known risk factor for the isolation of PNSSP although otitis-prone or recurrent AOM cases frequently require repeated courses of antibiotic treatment. In order to evaluate the chronological alteration of S. pneumoniae during...
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