Article
mAtNOS1 regulates mitochondrial functions and apoptosis of human neuroblastoma cells.
Biochimica et biophysica acta - 1 Jun 2008
Parihar Mordhwaj S, Parihar Arti, Chen Zhonghai, Nazarewicz Rafal, Ghafourifar Pedram
Abstract excerpt
mAtNOS1 is a novel gene recently reported in mammalian cells with functions that are not fully understood. The present study generated human neuroblastoma SHSY cells over- and underexpressing mAtNOS1 and shows that mAtNOS1 is involved in regulating mitochondrial nitric oxide, mitochondrial transmembrane potential, protein tyrosine nitration, cytochrome c release, and apoptosis of those cells.
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