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Loss of Egg Yolk Genes in Mammals and the Origin of Lactation and Placentation

14 Mar 2008

Abstract excerpt

Embryonic development in nonmammalian vertebrates depends entirely on nutritional reserves that are predominantly derived from vitellogenin proteins and stored in egg yolk. Mammals have evolved new resources, such as lactation and placentation, to nourish their developing and early offspring. However, the evolutionary timing and molecular events associated with this major phenotypic transition are not known. By...

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PMID: 18351802
DOI: 10.1371/journal.pbio.0060063

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