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Article

Divergent physical activity and novel alternative responses to high fat feeding in polygenic fat and lean mice.

Behavior genetics - 1 May 2008

Simoncic Matjaz, Horvat Simon, Stevenson Paula L, Bünger Lutz, Holmes Megan C, Kenyon Christopher J, Speakman John R, Morton Nicholas M

Abstract excerpt

We determined whether altered physical activity levels might underlie the contrasting adiposity of a divergently selected polygenic murine model of metabolic syndrome (Fat; F) and leanness (Lean; L) mice. We measured physical activity with a long term running wheel experiment and performed an additional high fat diet intervention. Further, we measured posture allocation by visual monitoring within the home cage...

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PMID: 18347969
DOI: 10.1007/s10519-008-9199-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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