Article
Influence of angiotensin I-converting enzyme polymorphism on development of post-transplant erythrocytosis in renal graft recipients.
Clinical transplantation - 1 Jan 2000
Kedzierska Karolina, Kabat-Koperska Joanna, Safranow Krzysztof, Domański Maciej, Gołembiewska Edyta, Bober Joanna, Bohatyrewicz Romuald, Ciechanowski Kazimierz
Abstract excerpt
BACKGROUND: Post-transplant erythrocytosis (PTE) is estimated at 5-20%. Angiotensin II generated by angiotensin I-converting enzyme (ACE) stimulates erythropoiesis. The highest activity of ACE is observed in DD genotype. The question arises if ACE gene polymorphism influences PTE. METHODS: One-year prospective study included 89 kidney recipients (28 women and 61 men). RESULTS: Thirty-four (38%) recipients proved...
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