Article
Abnormal indices of cell cycle activity in schizophrenia and their potential association with oligodendrocytes.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2008
Katsel Pavel, Davis Kenneth L, Li Celeste, Tan Weilun, Greenstein Elizabeth, Kleiner Hoffman Lisa B, Haroutunian Vahram
Abstract excerpt
The goal of this study was to determine what signaling pathways may elicit myelin-specific gene expression deficits in schizophrenia (SZ). Microarray analyses indicated that genes associated with canonical cell cycle pathways were significantly affected in the anterior cingulate gyrus (ACG), the region exhibiting the most profound myelin-specific gene expression changes, in persons with SZ (N=16) as compared with...
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