Article
[Mutations of the Epstein-Barr virus LMP1 gene mutations in Russian patients with lymphoid pathology and healthy individuals].
Voprosy virusologii - 1 Jan 2000
Pavlish O A, Diduk S V, Smirnova K V, Shcherbak L N, Goncharova E V, Shalginskikh N A, Arkhipov V V, Kichigina M Iu, Stepina V N, Belousova N V, Osmanov E A, Iakovleva L S, Gurtsevich V E
Abstract excerpt
Epstein-Barr virus (EBV) is an etiological agent of a number of benign and malignant human diseases, such as infectious mononucleosis (IM), Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL). EBV latent membrane protein 1 (LMP1) gene (recognized as a viral oncoprotein) of various clinical and geographical origin was found to have different types of amino acid mutations affecting its biological activity....
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