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Article

Polymorphisms of the luteinizing hormone/chorionic gonadotropin receptor gene: association with maldescended testes and male infertility.

Pharmacogenetics and genomics - 1 Mar 2008

Simoni Manuela, Tüttelmann Frank, Michel Caroline, Böckenfeld Yvonne, Nieschlag Eberhard, Gromoll Jörg

Abstract excerpt

OBJECTIVE: Maldescended testes are the most common genital anomaly in newborns and are associated with testicular malignancy and infertility. As the inguinoscrotal phase of testis descent is androgen-dependent and requires integrity of the luteinizing hormone/chorionic gonadotropin receptor (LHCGR), we investigated whether nonsynonymous polymorphisms of the LHCGR gene are associated with maldescended testes....

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Source

Identifiers

PMID: 18300940
DOI: 10.1097/FPC.0b013e3282f4e98c

Genes

LHCGR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of the luteinizing hormone/chorionic gonadotropin receptor gene: association with maldescended testes and male infertility.PMID 18300940Read ↗

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