Article
Lung cancer risk associated with Thr495Pro polymorphism of GHR in Chinese population.
Japanese journal of clinical oncology - 1 Apr 2008
Cao Guochun, Lu Hongna, Feng Jifeng, Shu Jian, Zheng Datong, Hou Yayi
Abstract excerpt
The incidence of lung cancer has been increasing over recent decades. Previous studies showed that polymorphisms of the genes involved in carcinogen-detoxication, DNA repair and cell cycle control comprise risk factors for lung cancer. Recent observations revealed that the growth hormone receptor (GHR) might play important roles in carcinogenesis and Rudd et al. found that the Thr495Pro polymorphism of GHR was...
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