Article
Characterization of a cis-acting element involved in cell-specific expression of the zebrafish brain aromatase gene.
Molecular reproduction and development - 1 Oct 2008
Le Page Yann, Menuet Arnaud, Kah Olivier, Pakdel Farzad
Abstract excerpt
The cytochrome P450 Aromatase is the key enzyme catalyzing the conversion of androgens into estrogens. In zebrafish, the brain aromatase is encoded by cyp19b. Expression of cyp19b is restricted to radial glial cells bordering forebrain ventricles and is strongly stimulated by estrogens during development. At the promoter level, we have previously shown that an estrogen responsive element (ERE) is required for...
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