DNA markers and biological vulnerability markers in families multiply affected with schizophrenia.

Abstract excerpt

A family is reported in which the monozygotic co-twin of a schizophrenic proband was diagnosed bipolar 1 and their mother had a history of unipolar major depression. Although their clinical manifestations varied, the ill members of this family shared an abnormality in P300 not found in the asymptomatic siblings. In 14 families, linkage to the 5q11-13 region was excluded when affection status was defined solely by...

Topics

• Arousal
• DNA
• Evoked Potentials, Auditory
• Eye Movements
• Genetic Linkage
• Genetic Markers
• Humans
• Models, Genetic
• Pedigree
• Phenotype
• Risk Factors
• Schizophrenia