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Article

Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain.

BMC neuroscience - 14 Feb 2008

Bachstetter Adam D, Pabon Mibel M, Cole Michael J, Hudson Charles E, Sanberg Paul R, Willing Alison E, Bickford Paula C, Gemma Carmelina

Abstract excerpt

BACKGROUND: Neurogenesis continues to occur throughout life but dramatically decreases with increasing age. This decrease is mostly related to a decline in proliferative activity as a result of an impoverishment of the microenvironment of the aged brain, including a reduction in trophic factors and increased inflammation. RESULTS: We determined that human umbilical cord blood mononuclear cells (UCBMC) given...

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Identifiers

PMID: 18275610
DOI: 10.1186/1471-2202-9-22
PMCID: PMC2268935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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