Article
Identification and geographic distribution of the ACE-1R mutation in the malaria vector Anopheles gambiae in south-western Burkina Faso, West Africa.
The American journal of tropical medicine and hygiene - 1 Feb 2008
Djogbénou Luc, Dabiré Roch, Diabaté Abdoulaye, Kengne Pierre, Akogbéto Martin, Hougard Jean Marc, Chandre Fabrice
Abstract excerpt
Resistance of Anopheles gambiae to organophosphate and carbamate insecticides was first reported in Côte d'Ivoire, West Africa. Subsequent studies revealed that it resulted from a single point mutation in the oxyanion hole of the acetycholinesterase enzyme (ace-1(R) mutation). We investigated the distribution and prevalence of the ace-1(R) mutation in An. gambiae s.l. populations from seven locations in...
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