Article
Effects of pyridine exposure upon structural lipid metabolism in Swiss Webster mice.
Chemical research in toxicology - 1 Mar 2008
Wheelock Craig E, Forshed Jenny, Goto Susumu, Hammock Bruce D, Newman John W
Abstract excerpt
Pyridine is a prototypical inducer of cytochrome P450 (CYP) 2E1, an enzyme associated with cellular oxidative stress and membrane damage. To better understand the effect of this treatment on cellular lipids, the influence of pyridine exposure (100 mg/kg/day i.p. for 5 days) on fatty acids, fatty esters, and fatty alcohol ethers in brain, heart, liver, and adipose tissue from male Swiss Webster mice was...
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