Article
Blunted beta-adrenoceptor-mediated fat oxidation in overweight subjects: a role for the hormone-sensitive lipase gene.
Metabolism: clinical and experimental - 1 Mar 2008
Jocken Johan W E, Blaak Ellen E, van der Kallen Carla J H, van Baak Marleen A, Saris Wim H M
Abstract excerpt
Obesity is associated with blunted beta-adrenoceptor-mediated lipolysis and fat oxidation, which persist after weight reduction. We investigated whether dinucleotide (CA)(n) repeat polymorphisms in intron 6 (i6) or 7 (i7) and a C-60G promoter substitution of the hormone-sensitive lipase (HSL) gen...
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