Article
Periodic re-emergence of endemic strains with strong epidemic potential-a proposed explanation for the 2004 Indonesian dengue epidemic.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2008
Ong Swee Hoe, Yip Jin Teen, Chen Yen Liang, Liu Wei, Harun Syahrial, Lystiyaningsih Erlin, Heriyanto Bambang, Beckett Charmagne G, Mitchell Wayne P, Hibberd Martin L, Suwandono Agus, Vasudevan Subhash G, Schreiber Mark J
Abstract excerpt
Indonesia experienced a severe dengue epidemic in the first quarter of 2004 with 58,301 cases and 658 deaths reported to the WHO. All four dengue virus (DENV) serotypes were detected, with DENV-3 the predominant strain. To ascertain the molecular epidemiology of the DENV associated with the epidemic, complete genomes of 15 isolates were sequenced from patient serum collected in Jakarta during the epidemic, and...
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