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Article

A functional variant of the tryptophan hydroxylase 2 gene impacts working memory: a genetic imaging study.

Biological psychology - 1 Sept 2008

Reuter M, Esslinger C, Montag C, Lis S, Gallhofer B, Kirsch P

Abstract excerpt

Imaging studies have demonstrated that prefrontal and parietal regions are activated during working memory (WM) tasks. Recently some molecular genetic studies reported associations between a functional promoter polymorphism of the tryptophan hydroxylase 2 gene (TPH2), that regulates the synthesis of serotonin, and attention. In 49 healthy Caucasian subjects the role of the TPH2 -703 G/T polymorphism for WM was...

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Source

Identifiers

PMID: 18234415
DOI: 10.1016/j.biopsycho.2007.12.002

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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