Article
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification.
BMC bioinformatics - 28 Jan 2008
Kouskoumvekaki Irene, Yang Zhiyong, Jónsdóttir Svava O, Olsson Lisbeth, Panagiotou Gianni
Abstract excerpt
BACKGROUND: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produce the 6- methyl salicylic acid polyketide molecule) for application in metabolic engineering. RESULTS: More than 450 metabolites were detected and subsequently used in the analysis. Our approach consists of two analytical steps of the...
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