Article
Difference in characteristics of APC mutations between colonic and extracolonic tumors of FAP patients: variations with phenotype.
International journal of cancer - 1 Jun 2008
Miyaki Michiko, Yamaguchi Tatsuro, Iijima Takeru, Takahashi Keiichi, Matsumoto Hiroshi, Yasutome Michiya, Funata Nobuaki, Mori Takeo
Abstract excerpt
To clarify the differences in characteristics of adenomatous polyposis coli (APC) mutations between colorectal tumors from various phenotypes of familial adenomatous polyposis (FAP) and between colorectal and extracolonic tumors, we analyzed APC mutations in 86 colorectal tumors from FAP patients including profuse, sparse and attenuated types, 23 sporadic colorectal tumors and 40 FAP extracolonic tumors including...
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