Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype.

Oncogene - 5 Jun 2008

Oxmann D, Held-Feindt J, Stark A M, Hattermann K, Yoneda T, Mentlein R

Abstract excerpt

Endoglin is a cell-surface adhesion protein as well as a coreceptor for transforming growth factor-beta (TGF-beta). It is located on endothelial and few other cells, but also found on certain tumor cells. Brain metastatic breast tumor cells derived from the MDA-MB-231 cell line heavily express endoglin in contrast to the corresponding parental ones. To clarify whether this determines their invasive phenotype, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Endoglin
Share to Glioma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Matrix Metalloproteinase 1

Share to Neoplasm Invasiveness

Share to Neoplasm Metastasis

Share to Receptors, Cell Surface

Share to Transforming Growth Factor beta

Source

Identifiers

PMID: 18223685
DOI: 10.1038/sj.onc.1211025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endoglin expression in metastatic breast cancer cells enhances their invasive phenotype.PMID 18223685Read ↗

Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanomaSemantic proximity Read ↗

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell LinesSemantic proximity Read ↗

Characterization of murine S-endoglin isoform and its effects on tumor development.Semantic proximity Read ↗

Endoglin as an Adhesion Molecule in Mature and Progenitor Endothelial Cells: A Function Beyond TGF-βSemantic proximity Read ↗

Molecular determinants of glioma cell migration and invasionSemantic proximity Read ↗

ADAM-9 is a novel mediator of tenascin-C-stimulated invasiveness of brain tumor–initiating cellsSemantic proximity Read ↗

Expression profiling reveals genes associated with transendothelial migration of tumor cells: A functional role for αvβ3 integrinSemantic proximity Read ↗

Endoglin: An accessory component of the TGF‐β‐binding receptor‐complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignanciesSemantic proximity Read ↗

Indirubins Decrease Glioma Invasion by Blocking Migratory Phenotypes in Both the Tumor and Stromal Endothelial Cell CompartmentsSemantic proximity Read ↗

Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiformeSemantic proximity Read ↗

Dissecting glioma invasion: interrelation of adhesion, migration and intercellular contacts determine the invasive phenotype.Semantic proximity Read ↗

HEMCAM/CD146 downregulates cell surface expression of β1 integrinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.