Article
Membrane-proximal cytoplasmic domain of Moloney murine leukemia virus envelope tail facilitates fusion.
Experimental and molecular pathology - 1 Feb 2008
Rozenberg-Adler Yanina, Conner John, Aguilar-Carreno Hector, Chakraborti Samitabh, Dimitrov Dimiter S, Anderson W French
Abstract excerpt
Removal of the R peptide (residues 617-632) from the Moloney murine leukemia virus (MoMuLV) envelope protein (Env) cytoplasmic tail potentiates fusion. We examined the role of the membrane-proximal cytoplasmic domain (598-616) of the MoMuLV Env in the Env-mediated membrane fusion and incorporation. The Env truncated at 616 exhibits maximum fusogenicity in cell-to-cell fusion assay. By comparison, full tail Env...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
