New hypotheses in the genetics of psoriasis and other 'complex' diseases.

Abstract excerpt

Psoriasis is a complex genetic disorder in which the disease, according to the current concept, is caused by the interplay of many different genes. However, recent genetic studies indicate that the location of these genes varies considerably among populations and families, raising the question of how the same phenotype can be induced by such variable genetic linkages. To circumvent these discrepancies we propose...

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