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Article

Simian Immunodeficiency Virus SIVagm Dynamics in African Green Monkeys

24 Jan 2008

Abstract excerpt

The mechanisms underlying the lack of disease progression in natural simian immunodeficiency virus (SIV) hosts are still poorly understood. To test the hypothesis that SIV-infected African green monkeys (AGMs) avoid AIDS due to virus replication occurring in long-lived infected cells, we infected six animals with SIVagm and treated them with potent antiretroviral therapy [ART; 9-R-(2-phosphonomethoxypropyl)...

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PMID: 18216122
DOI: 10.1128/jvi.02402-07

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