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Article

DNA adducts and other biological markers in risk assessment for environmental carcinogens.

Annali dell'Istituto superiore di sanita - 1 Jan 1991

Perera F, Mayer J, Santella R M, Brenner D, Tsai W Y, Brandt-Rauf P, Hemminki K

Abstract excerpt

In order to validate a number of biologic markers as indicators of effective dose or potential risk, we have applied them in related cross-sectional, longitudinal and case-control studies. Biologic markers such as carcinogen-DNA adducts and activated oncogenes have already provided insights into mechanisms of chemical carcinogenesis. They have also given information regarding the extent of interindividual...

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PMID: 1820734

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