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Article

Potential predictive markers of response to EGFR-targeted therapies in colorectal cancer.

Critical reviews in oncology/hematology - 1 Apr 2008

Spano Jean Philippe, Milano Gérard, Vignot Stéphane, Khayat David

Abstract excerpt

The importance of the epidermal growth factor receptor (EGFR) axis in tumorigenesis and tumor progression makes it an attractive target for the development of anticancer therapies. Strategies aimed at inhibiting the EGFR pathway included different classes of compounds, with monoclonal antibodies and tyrosine kinase inhibitors being the most widely-investigated agents in colorectal cancer. Although anti-EGFR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18206383
DOI: 10.1016/j.critrevonc.2007.11.005

Genes

EGFR
KRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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