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Novel Blood-Based, Five-Gene Biomarker Set for the Detection of Colorectal Cancer

15 Jan 2008

Abstract excerpt

PURPOSE: We applied a unique method to identify genes expressed in whole blood that can serve as biomarkers to detect colorectal cancer (CRC). EXPERIMENTAL DESIGN: Total RNA was isolated from 211 blood samples (110 non-CRC, 101 CRC). Microarray and quantitative real-time PCR were used for biomarker screening and validation, respectively. RESULTS: From a set of 31 RNA samples (16 CRC, 15 controls), we selected 37...

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PMID: 18203981
DOI: 10.1158/1078-0432.ccr-07-1801

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