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Article

Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders.

Human molecular genetics - 1 May 2008

Mercader Josep Maria, Saus Ester, Agüera Zaida, Bayés Mònica, Boni Claudette, Carreras Anna, Cellini Elena, de Cid Rafael, Dierssen Mara, Escaramís Geòrgia, Fernández-Aranda Fernando, Forcano Laura, Gallego Xavier, González Juan Ramón, Gorwood Philip, Hebebrand Johannes, Hinney Anke, Nacmias Benedetta, Puig Anna, Ribasés Marta, Ricca Valdo, Romo Lucia, Sorbi Sandro, Versini Audrey, Gratacòs Mònica, Estivill Xavier

Abstract excerpt

Eating disorders (EDs) are complex psychiatric diseases that include anorexia nervosa and bulimia nervosa, and have higher than 50% heritability. Previous studies have found association of BDNF and NTRK2 to ED, while animal models suggest that other neurotrophin genes might also be involved in ea...

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Source

Identifiers

PMID: 18203754
DOI: 10.1093/hmg/ddn013

Genes

NTRK3
BDNF
NTRK2
CNTF
CNTFR
NGF
NGFR
NTF3
NTF4
NTRK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18203754-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders.PMID 18203754Read ↗

Role of the neurotrophin network in eating disorders' subphenotypes: body mass index and age at onset of the disease.Semantic proximity Read ↗

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