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Article

Functional UQCRC1 polymorphisms affect promoter activity and body lipid accumulation.

Obesity (Silver Spring, Md.) - 1 Dec 2007

Kunej Tanja, Wang Zeping, Michal Jennifer J, Daniels Tyler F, Magnuson Nancy S, Jiang Zhihua

Abstract excerpt

Obesity and type 2 diabetes constitute leading public health problems worldwide. Studies have shown that insulin resistance affiliated with these conditions is associated with skeletal muscle lipid accumulation, while the latter is associated with mitochondrial dysfunctions. However, the initiation and regulation of mitochondrial biogenesis rely heavily on approximately 1000 nuclear-encoded mitochondrial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18198295
DOI: 10.1038/oby.2007.344

Genes

UQCRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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