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Article

International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.

International journal of cancer - 1 May 2008

Metcalfe Kelly A, Birenbaum-Carmeli Daphna, Lubinski Jan, Gronwald Jacek, Lynch Henry, Moller Pal, Ghadirian Parviz, Foulkes William D, Klijn Jan, Friedman Eitan, Kim-Sing Charmaine, Ainsworth Peter, Rosen Barry, Domchek Susan, Wagner Teresa, Tung Nadine, Manoukian Siranoush, Couch Fergus, Sun Ping, Narod Steven A

Abstract excerpt

Several options for cancer prevention are available for women with a BRCA1 or BRCA2 mutation, including prophylactic surgery, chemoprevention and screening. The authors report on preventive practices in women with mutations from 9 countries and examine differences in uptake according to country. Women with a BRCA1 or BRCA2 mutation were contacted after receiving their genetic test result and were questioned...

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Source

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Identifiers

PMID: 18196574
DOI: 10.1002/ijc.23340
PMCID: PMC2936778

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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