Article
Guidelines for the clinical management of familial adenomatous polyposis (FAP).
Gut - 1 May 2008
Vasen H F A, Möslein G, Alonso A, Aretz S, Bernstein I, Bertario L, Blanco I, Bülow S, Burn J, Capella G, Colas C, Engel C, Frayling I, Friedl W, Hes F J, Hodgson S, Järvinen H, Mecklin J-P, Møller P, Myrhøi T, Nagengast F M, Parc Y, Phillips R, Clark S K, de Leon M Ponz, Renkonen-Sinisalo L, Sampson J R, Stormorken A, Tejpar S, Thomas H J W, Wijnen J
Abstract excerpt
BACKGROUND: Familial adenomatous polyposis (FAP) is a well-described inherited syndrome, which is responsible for <1% of all colorectal cancer (CRC) cases. The syndrome is characterised by the development of hundreds to thousands of adenomas in the colorectum. Almost all patients will develop CRC if they are not identified and treated at an early stage. The syndrome is inherited as an autosomal dominant trait and...
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