Article
The 5-HTTLPR polymorphism in South African healthy populations: a global comparison.
Journal of neural transmission (Vienna, Austria : 1996) - 1 May 2008
Esau Luke, Kaur Mandeep, Adonis Lucinda, Arieff Zainunisha
Abstract excerpt
The serotonin transporter promoter length polymorphism (5-hydroxytryptamine transporter length polymorphism, 5-HTTLPR) in serotonin transporter gene has been implicated in numerous psychiatric disorders. Having a high affinity for the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT), serotonin transporter controls the duration, availability and signaling capacity of 5-HT in the synapse. Association studies...
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