Article
Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools.
Mutation research - 1 Mar 2008
Zhu Yong, Hoffman Aaron, Wu Xifeng, Zhang Heping, Zhang Yawei, Leaderer Derek, Zheng Tongzhang
Abstract excerpt
Bioinformatic tools are widely utilized to predict functional single nucleotide polymorphisms (SNPs) for genotyping in molecular epidemiological studies. However, the extent to which these approaches are mirrored by epidemiological findings has not been fully explored. In this study, we first surveyed SNPs examined in case-control studies of lung cancer, the most extensively studied cancer type. We then computed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
