Detection of Y-chromosome in gonadal tumours using fluorescence in situ hybridization: diagnostic value in intersex conditions including older patients with clinically unsuspected androgen insensitivity syndrome.

doi:10.1111/j.1365-2559.2007.02927.x

Article

Detection of Y-chromosome in gonadal tumours using fluorescence in situ hybridization: diagnostic value in intersex conditions including older patients with clinically unsuspected androgen insensitivity syndrome.

Histopathology - 1 Jan 2008

Stewart C J R, Baker E, Beaton C, Crook M, Peverall J, Wallace S

Abstract excerpt

AIMS: To evaluate fluorescence in situ hybridization (FISH) for SRY, the testis-determining gene on the Y-chromosome, in gonadal specimens from patients with intersex disorders including two older individuals presenting with Sertoli cell adenomas and clinically unsuspected androgen insensitivity syndrome (AIS). METHODS AND RESULTS: FISH, using probes for SRY and the X-centromere, was performed on two Sertoli cell...

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Detection of Y-chromosome in gonadal tumours using fluorescence in situ hybridization: diagnostic value in intersex conditions including older patients with clinically unsuspected androgen insensitivity syndrome.

Abstract excerpt

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