Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Incomplete masculinisation of XX subjects carrying the SRY gene on an inactive X chromosome.

Journal of medical genetics - 1 Jun 1999

Kusz K, Kotecki M, Wojda A, Szarras-Czapnik M, Latos-Bielenska A, Warenik-Szymankiewicz A, Ruszczynska-Wolska A, Jaruzelska J

Abstract excerpt

46,XX subjects carrying the testis determining SRY gene usually have a completely male phenotype. In this study, five very rare cases of SRY carrying subjects (two XX males and three XX true hermaphrodites) with various degrees of incomplete masculinisation were analysed in order to elucidate the cause of sexual ambiguity despite the presence of the SRY gene. PCR amplification of 20 Y chromosome specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disorders of Sex Development
Share to Dosage Compensation, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Sex Determination Processes

Share to Sex-Determining Region Y Protein

Share to Translocation, Genetic

Share to X Chromosome

Share to Y Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 10874632
PMCID: PMC1734388

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Incomplete masculinisation of XX subjects carrying the SRY gene on an inactive X chromosome.PMID 10874632Read ↗

The sole presence of the testis-determining region of the Y chromosome (SRY) in 46,XX patients is associated with phenotypic variability.Semantic proximity Read ↗

SRY gene transferred to the long arm of the X chromosome in a Y-positive XX true hermaphroditeSemantic proximity Read ↗

CLINICAL AND MOLECULAR ANALYSIS OF XX SEX REVERSED PATIENTSSemantic proximity Read ↗

SRY-negative true hermaphrodites and an XX male in two generations of the same family.Semantic proximity Read ↗

True hermaphroditism with ambiguous genitalia due to a complicated mosaic karyotype: Clinical features, cytogenetic findings, and literature reviewSemantic proximity Read ↗

Three new 46,XX male patients: a clinical, cytogenetic and molecular analysis.Semantic proximity Read ↗

Combined Leydig cell and Sertoli cell dysfunction in 46,XX males lacking the sex determining region Y gene.Semantic proximity Read ↗

46,XX sex reversal.Semantic proximity Read ↗

Clinical, molecular and cytogenetic analysis of 46, XX testicular disorder of sex development with SRY-positive.Semantic proximity Read ↗

Clinical and anatomical spectrum in XX sex reversed patients. Relationship to the presence of Y specific DNA-sequences.Semantic proximity Read ↗

SRY-negative 46,XX male with normal genitals, complete masculinization and infertility.Semantic proximity Read ↗

The role of the sex-determining region of the Y chromosome (SRY) in the etiology of 46,XX true hermaphroditismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.