Article
3D radiotherapy can be safely combined with sandwich systemic gemcitabine chemotherapy in the management of pancreatic cancer: factors influencing outcome.
International journal of radiation oncology, biology, physics - 1 Apr 2008
Spry Nigel, Harvey Jennifer, Macleod Craig, Borg Martin, Ngan Samuel Y, Millar Jeremy L, Graham Peter, Zissiadis Yvonne, Kneebone Andrew, Carroll Susan, Davies Terri, Reece William H H, Iacopetta Barry, Goldstein David
Abstract excerpt
PURPOSE: The aim of this Phase II study was to examine whether concurrent continuous infusion 5-fluorouracil (CI 5FU) plus three-dimensional conformal planning radiotherapy sandwiched between gemcitabine chemotherapy is effective, tolerable, and safe in the management of pancreatic cancer. METHODS AND MATERIALS: Patients were enrolled in two strata: (1) resected pancreatic cancer at high risk of local relapse...
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